CEACAM5 HCT116
CBP74687
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| I. Background | |
| CEACAM5(癌胚抗原相关细胞黏附分子5)即临床上常说的癌胚抗原(CEA),是一种GPI锚定的细胞表面糖蛋白。它在正常组织中低表达,但在结直肠癌、胃癌、肺癌等多种上皮性肿瘤中高表达,其血清水平是监测肿瘤治疗反应和复发的重要标志物。同时,它作为细胞黏附分子参与肿瘤进展,也是抗体药物和肿瘤成像的潜在靶点。 | |
| II. Description | |
| CEACAM5 HCT116 细胞,在 HCT116 细胞的基础上,稳定表达 CEACAM5。 | |
| III. Introduction | |
| Expressed gene: | CEACAM5 |
| Host Cell: | HCT116 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | McCoy's 5A + 10% FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
Figure 1. Recombinant CEACAM5 HCT116 constitutively expressing CEACAM5. |
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